Scientific Director | Head of Biomedical Image Informatics Group, Biomedical Image Informatics
buehler(at)vrvis.at +43 1 908 98 92 401Together with partners from science (Wulf Haubensack Laboratory Meduni Vienna, formerly IMP Vienna) and industry (Boehringer Ingelheim), the Biomedical Image Informatics research group of VRVis developed BrainTrawler - a web-based visual analytics tool that allows real-time access to very large data ("spatial index"): braintrawler.vrvis.at
For the first time, this tool combines several open brain data sets from mice and humans in one tool and enables neuroscientists to get an initial overview of what is in which data via a low-threshold user interface - the basis for neuroscientific research work.
BrainTrawler focuses on visualization techniques and interactivity to directly visualize the information contained in the data. BrainTrawler is also designed for common neuroscience workflows and allows users to examine gene expression data and the brain connectome for specific brain regions - for example, to understand the underlying dynamics for a particular human or animal behavior. Users can also use BrainTrawler to recognize patterns in gene expression, investigate combinations of gene data and structural and functional relationships in the brain. Comprehensive guides to BrainTrawler's datasets and capabilities help researchers quickly orient themselves and fully utilize its capabilities - a significant contribution to supporting and accelerating brain research.
Application for neurobiological data
BrainTrawler is a web-based framework for analyzing heterogeneous neurobiological data from mice and humans. Using spatial indexing, we enable the analysis of gene expression data and complex brain networks in real time. The assignment of data to hierarchically organized anatomical structures enables the search on different anatomical levels. Together with intuitive network visualization, iterative visual queries and quantitative information, BrainTrawler enables the genetic dissection of multimodal networks on a local/global level in a spatial context.
Unique collection of multiple, public brain datasets
BrainTrawler Lite bundles multiple open brain datasets in one tool for the first time: a major work facilitator for neuroscience. A unique collection of public neuroscience datasets of Brain Transcriptomic And Connectivity Data (BrainTACO) including (almost) brain-wide scRNA seq data.
Multi-modal and multi-scale analysis
BrainTrawler's multi-modal analysis enables the joint exploration of different modalities such as microarray gene expression data or connectivity data. Multi-scale analysis enables the joint analysis of data at regional and voxel level by mapping to the same reference space.
Real-time calculations on large amounts of data
Real-time calculations on large amounts of data using our spatial indexing technology. VRVis has been developing high-performance, data-driven solutions for neuroscience for around 25 years.
License information and information about collaborating on a joint research project can be obtained on request. Please contact Dr. Katja Bühler or DI Dr. Gerd Hesina via products(at)vrvis.at!